Epigenetics

DNA methylation is an epigenetic mechanism used by higher eukaryotes and involved in e.g. gene expression, X-Chromosome inactivating, imprinting, and gene silencing of germline specific gene and repetitive elements.

Requirements

Before diving into this topic, we recommend you to have a look at:

Material

You can view the tutorial materials in different languages by clicking the dropdown icon next to the slides () and tutorial () buttons below.
Lesson Slides Hands-on Recordings Input dataset Workflows
ATAC-Seq data analysis
DNA Methylation data analysis
Formation of the Super-Structures on the Inactive X
ChIP-seq
Hi-C analysis of Drosophila melanogaster cells using HiCExplorer
Identification of the binding sites of the T-cell acute lymphocytic leukemia protein 1 (TAL1)
ChIP-seq
Infinium Human Methylation BeadChip
Introduction to ChIP-Seq data analysis
Introduction to DNA Methylation data analysis

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Editorial Board

This material is reviewed by our Editorial Board:

orcid logoLucille Delisle avatar Lucille Delisleorcid logoFlorian Heyl avatar Florian HeylJoachim Wolff avatar Joachim WolffDevon Ryan avatar Devon Ryan

Contributors

This material was contributed to by:

orcid logoKatarzyna Kamieniecka avatar Katarzyna Kamienieckaorcid logoMo Heydarian avatar Mo Heydarianorcid logoFlorian Heyl avatar Florian HeylLeily Rabbani avatar Leily RabbaniJoachim Wolff avatar Joachim WolffFriederike Dündar avatar Friederike Dündarorcid logoLucille Delisle avatar Lucille Delisleorcid logoBjörn Grüning avatar Björn Grüningorcid logoHelena Rasche avatar Helena RascheMehmet Tekman avatar Mehmet TekmanAnup Kumar avatar Anup Kumarorcid logoYvan Le Bras avatar Yvan Le BrasFidel Ramirez avatar Fidel Ramirezorcid logoMaria Doyle avatar Maria Doyleorcid logoPavankumar Videm avatar Pavankumar VidemNiall Beard avatar Niall BeardMélanie Petera avatar Mélanie Peteraorcid logoKhaled Jum'ah avatar Khaled Jum'ahorcid logoAnika Erxleben avatar Anika Erxlebenorcid logoKrzysztof Poterlowicz avatar Krzysztof PoterlowiczVivek Bhardwaj avatar Vivek Bhardwajorcid logoNicola Soranzo avatar Nicola Soranzoorcid logoSaskia Hiltemann avatar Saskia HiltemannTorsten Houwaart avatar Torsten Houwaartorcid logoBérénice Batut avatar Bérénice Batutorcid logoMallory Freeberg avatar Mallory FreebergDevon Ryan avatar Devon RyanEkaterina Polkh avatar Ekaterina Polkh

Funding

These individuals or organisations provided funding support for the development of this resource

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de.NBI
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UFR
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CRC992
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ELIXIR Europe